Myopathy with Concurrent Tadalafil and Simvastatin

Myopathy with Concurrent Tadalafil and Simvastatin

Blog Article

A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin.Muscle pain and penile erection disappeared seven days after CAP FRAME MAIN REAR interruption of therapy.This case demonstrates the interaction Pop! Rides of tadalafil with simvastatin resulting in myopathy.

Muscle damage could be attributed to the common metabolic way of these two drugs which is cytochrome P450 isoenzyme system.